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Nanophthalmos-Associated MYRF Gene Mutation Causes Ciliary Zonule Defects in Mice

PURPOSE: Patients with nanophthalmos who undergo intraocular surgery often present with abnormal ciliary zonules. In a previous study, we reported mutation in MYRF that is implicated in the pathogenesis of nanophthalmos. The aim of this study was to model the mutation in mice to explore the role of...

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Detalles Bibliográficos
Autores principales: Yu, Xiaowei, Sun, Nannan, Yang, Xue, Zhao, Zhenni, Su, Xiaoqian, Zhang, Jiamin, He, Yuqing, Lin, Yixiu, Ge, Jian, Fan, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937999/
https://www.ncbi.nlm.nih.gov/pubmed/33646289
http://dx.doi.org/10.1167/iovs.62.3.1