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Cigarette Smoke Triggers Loss of Corneal Endothelial Cells and Disruption of Descemet's Membrane Proteins in Mice

PURPOSE: To investigate changes at a molecular level in the mouse corneal endothelium (CE) exposed to chronic cigarette smoke (CS). METHODS: Pregnant mice (gestation days 18–20) were placed in a whole-body exposure smoking chamber, and a few days later pups were born. After 3.5 months of CS exposure...

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Detalles Bibliográficos
Autores principales: Ali, Muhammad, Khan, Shahid Y., Jang, Yura, Na, Chan Hyun, Talbot, C. Conover, Gottsch, John D., Handa, James T., Riazuddin, S. Amer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938020/
https://www.ncbi.nlm.nih.gov/pubmed/33651877
http://dx.doi.org/10.1167/iovs.62.3.3