In vitro complex formation of human PYRIN domain-only protein 3 prevented by self-oligomerization of ASC PYD domain

The formation of inflammasome complexes contributes inactivation of inflammatory caspases viz caspase 1, which is generally considered essential for the innate response. Three proteins constituted this inflammasome complex, such as Nod-like receptors (NLRP or AIM2), ASC possessing caspase-recruiting...

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Detalles Bibliográficos
Autores principales: Ahmed Bhat, Eijaz, Sajjad, Nasreena, Ahmad Tantray, Javeed, Hor, Yan-Yan, Rather, Irfan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938106/
https://www.ncbi.nlm.nih.gov/pubmed/33732046
http://dx.doi.org/10.1016/j.sjbs.2020.12.049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938106/
https://www.ncbi.nlm.nih.gov/pubmed/33732046
http://dx.doi.org/10.1016/j.sjbs.2020.12.049

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