Increased telomerase improves motor function and alpha-synuclein pathology in a transgenic mouse model of Parkinson’s disease associated with enhanced autophagy

Protective effects of the telomerase protein TERT have been shown in neurons and brain. We previously demonstrated that TERT protein can accumulate in mitochondria of Alzheimer’s disease (AD) brains and protect from pathological tau in primary mouse neurons. This prompted us to employ telomerase act...

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Detalles Bibliográficos
Autores principales: Wan, Tengfei, Weir, Emma J., Johnson, Mary, Korolchuk, Viktor I., Saretzki, Gabriele C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938226/
https://www.ncbi.nlm.nih.gov/pubmed/33188884
http://dx.doi.org/10.1016/j.pneurobio.2020.101953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938226/
https://www.ncbi.nlm.nih.gov/pubmed/33188884
http://dx.doi.org/10.1016/j.pneurobio.2020.101953

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