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Ginaton injection alleviates cisplatin-induced renal interstitial fibrosis in rats via inhibition of apoptosis through regulation of the p38MAPK/TGF-β1 and p38MAPK/HIF-1α pathways

Ginaton injection (Ginkgo biloba extract; GBE) has been reported to protect against cisplatin-induced acute renal failure in rats. In the present study, the effects and molecular mechanisms of GBE on cisplatin-induced renal interstitial fibrosis were evaluated using a rat model. The rats were intrap...

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Detalles Bibliográficos
Autores principales: Liang, Taolin, Wei, Chongying, Lu, Sisi, Qin, Mengyuan, Qin, Guiming, Zhang, Yansong, Zhong, Xiaobin, Zou, Xiaoqin, Yang, Yufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938297/
https://www.ncbi.nlm.nih.gov/pubmed/33692901
http://dx.doi.org/10.3892/br.2021.1414