Molecular Mechanisms of Leukocyte Migration and Its Potential Targeting—Lessons Learned From MKL1/SRF-Related Primary Immunodeficiency Diseases

Megakaryoblastic leukemia 1 (MKL1) deficiency is one of the most recently discovered primary immunodeficiencies (PIDs) caused by cytoskeletal abnormalities. These immunological “actinopathies” primarily affect hematopoietic cells, resulting in defects in both the innate immune system (phagocyte defe...

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Detalles Bibliográficos
Autores principales: Sprenkeler, Evelien G. G., Guenther, Carla, Faisal, Imrul, Kuijpers, Taco W., Fagerholm, Susanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938309/
https://www.ncbi.nlm.nih.gov/pubmed/33692789
http://dx.doi.org/10.3389/fimmu.2021.615477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938309/
https://www.ncbi.nlm.nih.gov/pubmed/33692789
http://dx.doi.org/10.3389/fimmu.2021.615477

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