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Building the Next Generation of Humanized Hemato-Lymphoid System Mice

Since the late 1980s, mice have been repopulated with human hematopoietic cells to study the fundamental biology of human hematopoiesis and immunity, as well as a broad range of human diseases in vivo. Multiple mouse recipient strains have been developed and protocols optimized to efficiently genera...

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Detalles Bibliográficos
Autores principales: Martinov, Tijana, McKenna, Kelly M., Tan, Wei Hong, Collins, Emily J., Kehret, Allie R., Linton, Jonathan D., Olsen, Tayla M., Shobaki, Nour, Rongvaux, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938325/
https://www.ncbi.nlm.nih.gov/pubmed/33692812
http://dx.doi.org/10.3389/fimmu.2021.643852