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Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with continuous neuronal loss. Treatment of clinical progression remains challenging due to lack of insights into inflammation-induced neurodegenerative pathways. Here, we show that an imbalance in the neuronal r...

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Detalles Bibliográficos
Autores principales: Woo, Marcel S., Ufer, Friederike, Rothammer, Nicola, Di Liberto, Giovanni, Binkle, Lars, Haferkamp, Undine, Sonner, Jana K., Engler, Jan Broder, Hornig, Sönke, Bauer, Simone, Wagner, Ingrid, Egervari, Kristof, Raber, Jacob, Duvoisin, Robert M., Pless, Ole, Merkler, Doron, Friese, Manuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938362/
https://www.ncbi.nlm.nih.gov/pubmed/33661276
http://dx.doi.org/10.1084/jem.20201290