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Acquisition of cancer stem cell capacities after spontaneous cell fusion

BACKGROUND: Cancer stem/Initiating cell (CS/IC) hypothesis argues that CS/ICs are responsible of tumour initiation, drug resistance, metastasis or disease relapse. Their detection in several cancers supports this concept. However, their origin is still misunderstood. Cell fusion is shown to take par...

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Detalles Bibliográficos
Autores principales: Merle, Candice, Lagarde, Pauline, Lartigue, Lydia, Chibon, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938600/
https://www.ncbi.nlm.nih.gov/pubmed/33678155
http://dx.doi.org/10.1186/s12885-021-07979-2