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Cumulative Genetic Risk and APOE ε4 Are Independently Associated With Dementia Status in a Multiethnic, Population-Based Cohort

OBJECTIVE: Alzheimer disease (AD) is a common and costly neurodegenerative disorder. A large proportion of AD risk is heritable, and many genetic risk factors have been identified. The objective of this study was to test the hypothesis that cumulative genetic risk of known AD markers contributed to...

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Detalles Bibliográficos
Autores principales: Bakulski, Kelly M., Vadari, Harita S., Faul, Jessica D., Heeringa, Steven G., Kardia, Sharon L.R., Langa, Kenneth M., Smith, Jennifer A., Manly, Jennifer J., Mitchell, Colter M., Benke, Kelly S., Ware, Erin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938646/
https://www.ncbi.nlm.nih.gov/pubmed/33688582
http://dx.doi.org/10.1212/NXG.0000000000000576