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Inhibition of interferon-stimulated gene 15 and lysine 48-linked ubiquitin binding to the SARS-CoV-2 papain-like protease by small molecules: In silico studies

The SARS-CoV-2 papain-like protease (PL(pro)) is a suitable target for drug development, and its deubiquitinating and deISGylating activities have also been reported. In this study, molecular docking was used to investigate the binding properties of a selection of dietary compounds and naphthalene-b...

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Detalles Bibliográficos
Autores principales: Pitsillou, Eleni, Liang, Julia, Hung, Andrew, Karagiannis, Tom C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938750/
https://www.ncbi.nlm.nih.gov/pubmed/33716308
http://dx.doi.org/10.1016/j.cplett.2021.138468