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Inhibition of interferon-stimulated gene 15 and lysine 48-linked ubiquitin binding to the SARS-CoV-2 papain-like protease by small molecules: In silico studies
The SARS-CoV-2 papain-like protease (PL(pro)) is a suitable target for drug development, and its deubiquitinating and deISGylating activities have also been reported. In this study, molecular docking was used to investigate the binding properties of a selection of dietary compounds and naphthalene-b...
Autores principales: | Pitsillou, Eleni, Liang, Julia, Hung, Andrew, Karagiannis, Tom C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938750/ https://www.ncbi.nlm.nih.gov/pubmed/33716308 http://dx.doi.org/10.1016/j.cplett.2021.138468 |
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