Striatal Afferent BDNF Is Disrupted by Synucleinopathy and Partially Restored by STN DBS

Preclinical studies show a link between subthalamic nucleus (STN) deep brain stimulation (DBS) and neuroprotection of nigrostriatal dopamine (DA) neurons, potentially through brain-derived neurotrophic factor (BDNF) signaling. However, the question of whether DBS of the STN can be disease-modifying...

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Detalles Bibliográficos
Autores principales: Miller, Kathryn M., Patterson, Joseph R., Kochmanski, Joseph, Kemp, Christopher J., Stoll, Anna C., Onyekpe, Christopher U., Cole-Strauss, Allyson, Steece-Collier, Kathy, Howe, Jacob W., Luk, Kelvin C., Sortwell, Caryl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939095/
https://www.ncbi.nlm.nih.gov/pubmed/33472823
http://dx.doi.org/10.1523/JNEUROSCI.1952-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939095/
https://www.ncbi.nlm.nih.gov/pubmed/33472823
http://dx.doi.org/10.1523/JNEUROSCI.1952-20.2020

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