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A pilot study evaluating GSK1070806 inhibition of interleukin-18 in renal transplant delayed graft function

INTRODUCTION: Delayed graft function (DGF) following renal transplantation is a manifestation of acute kidney injury (AKI) leading to poor long-term outcome. Current treatments have limited effectiveness in preventing DGF. Interleukin-18 (IL18), a biomarker of AKI, induces interferon-γ expression an...

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Detalles Bibliográficos
Autores principales: Wlodek, E., Kirkpatrick, R. B., Andrews, S., Noble, R., Schroyer, R., Scott, J., Watson, C. J. E., Clatworthy, M., Harrison, E. M., Wigmore, S. J., Stevenson, K., Kingsmore, D., Sheerin, N. S., Bestard, O., Stirnadel-Farrant, H. A., Abberley, L., Busz, M., DeWall, S., Birchler, M., Krull, D., Thorneloe, K. S., Weber, A., Devey, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939287/
https://www.ncbi.nlm.nih.gov/pubmed/33684160
http://dx.doi.org/10.1371/journal.pone.0247972