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A pilot study evaluating GSK1070806 inhibition of interleukin-18 in renal transplant delayed graft function
INTRODUCTION: Delayed graft function (DGF) following renal transplantation is a manifestation of acute kidney injury (AKI) leading to poor long-term outcome. Current treatments have limited effectiveness in preventing DGF. Interleukin-18 (IL18), a biomarker of AKI, induces interferon-γ expression an...
Autores principales: | Wlodek, E., Kirkpatrick, R. B., Andrews, S., Noble, R., Schroyer, R., Scott, J., Watson, C. J. E., Clatworthy, M., Harrison, E. M., Wigmore, S. J., Stevenson, K., Kingsmore, D., Sheerin, N. S., Bestard, O., Stirnadel-Farrant, H. A., Abberley, L., Busz, M., DeWall, S., Birchler, M., Krull, D., Thorneloe, K. S., Weber, A., Devey, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939287/ https://www.ncbi.nlm.nih.gov/pubmed/33684160 http://dx.doi.org/10.1371/journal.pone.0247972 |
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