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Serum lipoprotein–derived fatty acids regulate hypoxia-inducible factor

Oxygen regulates hypoxia-inducible factor (HIF) transcription factors to control cell metabolism, erythrogenesis, and angiogenesis. Whereas much has been elucidated about how oxygen regulates HIF, whether lipids affect HIF activity is un-known. Here, using cultured cells and two animal models, we de...

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Detalles Bibliográficos
Autores principales: Shao, Wei, Hwang, Jiwon, Liu, Chune, Mukhopadhyay, Debaditya, Zhao, Shan, Shen, Meng-Chieh, Selen, Ebru S., Wolfgang, Michael J., Farber, Steven A., Espenshade, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939398/
https://www.ncbi.nlm.nih.gov/pubmed/33109611
http://dx.doi.org/10.1074/jbc.RA120.015238