C-tag TNF: a reporter system to study TNF shedding

TNF is a highly pro-inflammatory cytokine that contributes not only to the regulation of immune responses but also to the development of severe inflammatory diseases. TNF is synthesized as a transmembrane protein, which is further matured via proteolytic cleavage by metalloproteases such as ADAM17,...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinci, Francesca, Gaidt, Moritz M., Jung, Christophe, Kuut, Gunnar, Jackson, Margaret A., Bauernfried, Stefan, Hornung, Veit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939438/
https://www.ncbi.nlm.nih.gov/pubmed/33082141
http://dx.doi.org/10.1074/jbc.RA120.015248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939438/
https://www.ncbi.nlm.nih.gov/pubmed/33082141
http://dx.doi.org/10.1074/jbc.RA120.015248

Ejemplares similares