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Inhibition of oxidative metabolism by nitric oxide restricts EMCV replication selectively in pancreatic beta-cells
Environmental factors, such as viral infection, are proposed to play a role in the initiation of autoimmune diabetes. In response to encephalomyocarditis virus (EMCV) infection, resident islet macrophages release the pro-inflammatory cytokine IL-1β, to levels that are sufficient to stimulate inducib...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939444/ https://www.ncbi.nlm.nih.gov/pubmed/33100269 http://dx.doi.org/10.1074/jbc.RA120.015893 |