Murine GFP-Mx1 forms nuclear condensates and associates with cytoplasmic intermediate filaments: Novel antiviral activity against VSV

Type I and III interferons induce expression of the “myxovirus resistance proteins” MxA in human cells and its ortholog Mx1 in murine cells. Human MxA forms cytoplasmic structures, whereas murine Mx1 forms nuclear bodies. Whereas both HuMxA and MuMx1 are antiviral toward influenza A virus (FLUAV) (a...

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Detalles Bibliográficos
Autores principales: Sehgal, Pravin B., Yuan, Huijuan, Scott, Mia F., Deng, Yan, Liang, Feng-Xia, Mackiewicz, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939456/
https://www.ncbi.nlm.nih.gov/pubmed/33077519
http://dx.doi.org/10.1074/jbc.RA120.015661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939456/
https://www.ncbi.nlm.nih.gov/pubmed/33077519
http://dx.doi.org/10.1074/jbc.RA120.015661

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