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Murine GFP-Mx1 forms nuclear condensates and associates with cytoplasmic intermediate filaments: Novel antiviral activity against VSV
Type I and III interferons induce expression of the “myxovirus resistance proteins” MxA in human cells and its ortholog Mx1 in murine cells. Human MxA forms cytoplasmic structures, whereas murine Mx1 forms nuclear bodies. Whereas both HuMxA and MuMx1 are antiviral toward influenza A virus (FLUAV) (a...
Autores principales: | Sehgal, Pravin B., Yuan, Huijuan, Scott, Mia F., Deng, Yan, Liang, Feng-Xia, Mackiewicz, Andrzej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939456/ https://www.ncbi.nlm.nih.gov/pubmed/33077519 http://dx.doi.org/10.1074/jbc.RA120.015661 |
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