α-Synuclein facilitates endocytosis by elevating the steady-state levels of phosphatidylinositol 4,5-bisphosphate

α-Synuclein (α-Syn) is a protein implicated in the pathogenesis of Parkinson's disease (PD). It is an intrinsically disordered protein that binds acidic phospholipids. Growing evidence supports a role for α-Syn in membrane trafficking, including, mechanisms of endocytosis and exocytosis, althou...

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Detalles Bibliográficos
Autores principales: Schechter, Meir, Atias, Merav, Abd Elhadi, Suaad, Davidi, Dana, Gitler, Daniel, Sharon, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939461/
https://www.ncbi.nlm.nih.gov/pubmed/33087443
http://dx.doi.org/10.1074/jbc.RA120.015319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939461/
https://www.ncbi.nlm.nih.gov/pubmed/33087443
http://dx.doi.org/10.1074/jbc.RA120.015319

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