Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the line 66 model of frontotemporal dementia

Synapse loss is associated with motor and cognitive decline in multiple neurodegenerative disorders, and the cellular redistribution of tau is related to synaptic impairment in tauopathies, such as Alzheimer's disease and frontotemporal dementia. Here, we examined the cellular distribution of t...

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Detalles Bibliográficos
Autores principales: Lemke, Nora, Melis, Valeria, Lauer, Dilyara, Magbagbeolu, Mandy, Neumann, Boris, Harrington, Charles R., Riedel, Gernot, Wischik, Claude M., Theuring, Franz, Schwab, Karima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939472/
https://www.ncbi.nlm.nih.gov/pubmed/33127647
http://dx.doi.org/10.1074/jbc.RA120.014890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939472/
https://www.ncbi.nlm.nih.gov/pubmed/33127647
http://dx.doi.org/10.1074/jbc.RA120.014890

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