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Neuroligin-2 dependent conformational activation of collybistin reconstituted in supported hybrid membranes

The assembly of the postsynaptic transmitter sensing machinery at inhibitory nerve cell synapses requires the intimate interplay between cell adhesion proteins, scaffold and adaptor proteins, and γ-aminobutyric acid (GABA) or glycine receptors. We developed an in vitro membrane system to reconstitut...

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Detalles Bibliográficos
Autores principales: Schäfer, Jonas, Förster, Lucas, Mey, Ingo, Papadopoulos, Theofilos, Brose, Nils, Steinem, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939476/
https://www.ncbi.nlm.nih.gov/pubmed/33127642
http://dx.doi.org/10.1074/jbc.RA120.015347