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Transcription factor NF-κB promotes acute lung injury via microRNA-99b-mediated PRDM1 down-regulation

Acute lung injury (ALI), is a rapidly progressing heterogenous pulmonary disorder that possesses a high risk of mortality. Accumulating evidence has implicated the activation of the p65 subunit of NF-κB [NF-κB(p65)] activation in the pathological process of ALI. microRNAs (miRNAs), a group of small...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Xie, Fei, Chen, Ruidong, Zhang, Zhen, Dai, Rujun, Zhao, Na, Wang, Rongxin, Sun, Yanhong, Chen, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939479/
https://www.ncbi.nlm.nih.gov/pubmed/33109608
http://dx.doi.org/10.1074/jbc.RA120.014861