Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure

Infiltration of peripheral immune cells after blood-brain barrier dysfunction causes severe inflammation after a stroke. Although the endothelial glycocalyx, a network of membrane-bound glycoproteins and proteoglycans that covers the lumen of endothelial cells, functions as a barrier to circulating...

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Detalles Bibliográficos
Autores principales: Ko, Kenta, Suzuki, Takehiro, Ishikawa, Ryota, Hattori, Natsuko, Ito, Risako, Umehara, Kenta, Furihata, Tomomi, Dohmae, Naoshi, Linhardt, Robert J., Igarashi, Kazuei, Toida, Toshihiko, Higashi, Kyohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939480/
https://www.ncbi.nlm.nih.gov/pubmed/33127645
http://dx.doi.org/10.1074/jbc.RA120.015105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939480/
https://www.ncbi.nlm.nih.gov/pubmed/33127645
http://dx.doi.org/10.1074/jbc.RA120.015105

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