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Ligand bias in receptor tyrosine kinase signaling

Ligand bias is the ability of ligands to differentially activate certain receptor signaling responses compared with others. It reflects differences in the responses of a receptor to specific ligands and has implications for the development of highly specific therapeutics. Whereas ligand bias has bee...

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Detalles Bibliográficos
Autores principales: Karl, Kelly, Paul, Michael D., Pasquale, Elena B., Hristova, Kalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939482/
https://www.ncbi.nlm.nih.gov/pubmed/33122191
http://dx.doi.org/10.1074/jbc.REV120.015190