Cargando…
Ligand bias in receptor tyrosine kinase signaling
Ligand bias is the ability of ligands to differentially activate certain receptor signaling responses compared with others. It reflects differences in the responses of a receptor to specific ligands and has implications for the development of highly specific therapeutics. Whereas ligand bias has bee...
Autores principales: | Karl, Kelly, Paul, Michael D., Pasquale, Elena B., Hristova, Kalina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939482/ https://www.ncbi.nlm.nih.gov/pubmed/33122191 http://dx.doi.org/10.1074/jbc.REV120.015190 |
Ejemplares similares
-
G protein–coupled receptor interactions with arrestins and GPCR kinases: The unresolved issue of signal bias
por: Chen, Qiuyan, et al.
Publicado: (2022) -
BY-kinases: Protein tyrosine kinases like no other
por: Hajredini, Fatlum, et al.
Publicado: (2022) -
Unveiling the human nitroproteome: Protein tyrosine nitration in cell signaling and cancer
por: Griswold-Prenner, Irene, et al.
Publicado: (2023) -
There’s more to death than life: Noncatalytic functions in kinase and pseudokinase signaling
por: Mace, Peter D., et al.
Publicado: (2021) -
Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer
por: Asangani, Irfan, et al.
Publicado: (2021)