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Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms

Some cancers originate from a single mutation event in a single cell. Blood cancers known as myeloproliferative neoplasms (MPNs) are thought to originate when a driver mutation is acquired by a hematopoietic stem cell (HSC). However, when the mutation first occurs in individuals and how it affects t...

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Detalles Bibliográficos
Autores principales: Van Egeren, Debra, Escabi, Javier, Nguyen, Maximilian, Liu, Shichen, Reilly, Christopher R., Patel, Sachin, Kamaz, Baransel, Kalyva, Maria, DeAngelo, Daniel J., Galinsky, Ilene, Wadleigh, Martha, Winer, Eric S., Luskin, Marlise R., Stone, Richard M., Garcia, Jacqueline S., Hobbs, Gabriela S., Camargo, Fernando D., Michor, Franziska, Mullally, Ann, Cortes-Ciriano, Isidro, Hormoz, Sahand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939520/
https://www.ncbi.nlm.nih.gov/pubmed/33621486
http://dx.doi.org/10.1016/j.stem.2021.02.001