STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells

The glioma associated oncogene-1 (GLI1), a downstream effector of the embryonic Hedgehog pathway, was detected in chronic lymphocytic leukemia (CLL), but not normal adult cells. GLI1 activating mutations were identified in 10% of patients with CLL. However, what induces GLI1 expression in GLI1-unmut...

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Detalles Bibliográficos
Autores principales: Rozovski, Uri, Harris, David M., Li, Ping, Liu, Zhiming, Jain, Preetesh, Manshouri, Taghi, Veletic, Ivo, Ferrajoli, Alessandra, Bose, Prithviraj, Thompson, Phillip, Jain, Nitin, Verstovsek, Srdan, Wierda, William, Keating, Michael J., Estrov, Zeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939524/
https://www.ncbi.nlm.nih.gov/pubmed/33747356
http://dx.doi.org/10.18632/oncotarget.27884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939524/
https://www.ncbi.nlm.nih.gov/pubmed/33747356
http://dx.doi.org/10.18632/oncotarget.27884

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