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Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology

Compelling evidence demonstrates that miR-193a-3p is a tumor suppressor microRNA in many cancer types, and its reduced expression is linked to cancer initiation and progression, metastasis, and therapy resistance. However, its mechanism of action is not consistently described between studies, and of...

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Detalles Bibliográficos
Autores principales: Telford, Bryony J., Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Stegink, Marieke, van den Bosch, Marion T.J., Alemdehy, Mir Farshid, van Pinxteren, Laurens A.H., Schaapveld, Roel Q.J., Janicot, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939530/
https://www.ncbi.nlm.nih.gov/pubmed/33747358
http://dx.doi.org/10.18632/oncotarget.27894