Cargando…

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology

Compelling evidence demonstrates that miR-193a-3p is a tumor suppressor microRNA in many cancer types, and its reduced expression is linked to cancer initiation and progression, metastasis, and therapy resistance. However, its mechanism of action is not consistently described between studies, and of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Telford, Bryony J., Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Stegink, Marieke, van den Bosch, Marion T.J., Alemdehy, Mir Farshid, van Pinxteren, Laurens A.H., Schaapveld, Roel Q.J., Janicot, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939530/ https://www.ncbi.nlm.nih.gov/pubmed/33747358 http://dx.doi.org/10.18632/oncotarget.27894

Ejemplares similares

Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic
por: van den Bosch, Marion T.J., et al.
Publicado: (2021)

P422: TARGETING THE WT1MUT-MIR-193A TRANSCRIPTIONAL AXIS WITH INT-1B3, A NOVEL LIPID NANOPARTICLE-FORMULATED MIR-193A-3P MIMIC IN ACUTE MYELOID LEUKEMIA
por: Yang, Xining, et al.
Publicado: (2023)

LIN92#19.3
Publicado: (1993)

Stop the dicing in hematopoiesis: What have we learned?
por: Alemdehy, Mir Farshid, et al.
Publicado: (2012)

Targeting Notch to overcome radiation resistance
por: Yahyanejad, Sanaz, et al.
Publicado: (2015)

The $^{191,193}$Hg and $^{191,193}$Au positon decays
por: Vieu, C, et al.
Publicado: (1976)

Preclinical testing of miRNA-193b-3p mimic in acute myeloid leukemias
por: Issa, Hasan, et al.
Publicado: (2023)

The real part of the proton-neutron scattering amplitude at 19.3 GeV/c
por: Bellettini, Giorgio, et al.
Publicado: (1965)

Configurations of superdeformed bands in $^{193}$Pb
por: Ducroux, L, et al.
Publicado: (1996)

Biological Function of MicroRNA193a-3p in Health and Disease
por: Grossi, Ilaria, et al.
Publicado: (2017)

P419: HARNESSING MIRNA-193B-3P MIMIC AS A POTENT THERAPEUTIC OPTION IN ACUTE MYELOID LEUKEMIA
por: Issa, Hasan, et al.
Publicado: (2023)

miR-193a-3p is a potential tumor suppressor in malignant pleural mesothelioma
por: Williams, Marissa, et al.
Publicado: (2015)

AB193. Rectourethral fistula
por: Jiang, Hai
Publicado: (2016)

Health Tract, No. 193: Bread
Publicado: (1865)

Health Tract, No. 193: Bread
Publicado: (1864)

MicroRNA-193b-3p regulates chondrogenesis and chondrocyte metabolism by targeting HDAC3
por: Meng, Fangang, et al.
Publicado: (2018)

193. Duration of Antimicrobial Therapy: The Impact of Defaults
por: Wrenn, Rebekah, et al.
Publicado: (2018)

Impact of tight glucose control on circulating 3-hydroxybutyrate in critically ill patients
por: Gunst, Jan, et al.
Publicado: (2021)

Prospective, observational study comparing automated and visual point-of-care urinalysis in general practice
por: van Delft, Sanne, et al.
Publicado: (2016)

Overall view of AA in Bld. 193
Publicado: (1980)

Overall view of AA (Bld 193)
Publicado: (1980)

Estimated GFR versus creatinine clearance for evaluation of recovery from acute kidney injury
por: Timmermans, P, et al.
Publicado: (2014)

Recovery from AKI by KDIGO criteria
por: Schrijvers, D, et al.
Publicado: (2014)

A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193
por: Ling, Elise M., et al.
Publicado: (2022)

Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers
por: Burvenich, Ingrid J. G., et al.
Publicado: (2016)

A Functional Screen Identifies Specific MicroRNAs Capable of Inhibiting Human Melanoma Cell Viability
por: Poell, Jos B., et al.
Publicado: (2012)

MiR-193-3p inhibits the malignant progression of atherosclerosis by targeting WDR5
por: Yang, Kai, et al.
Publicado: (2022)

RNAi-mediated knockdown of pituitary tumor-transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cells
por: Huang, S.Q., et al.
Publicado: (2012)

Inhibition of breast cancer metastasis by co-transfection of miR-31/193b-mimics
por: Hashemi, Zahra Sadat, et al.
Publicado: (2018)

Fibroblast growth factor 21 response to critical illness: effect of blood glucose control and relation with mitochondrial dysfunction, the integrated stress response and survival
por: Thiessen, S, et al.
Publicado: (2015)

Dipole bands and multi-particle excitations in $^{193}Pb$
por: Ducroux, L, et al.
Publicado: (1996)

Magnetic properties of superdeformed $^{193}$Hg and $^{195}$Ti nuclei
por: Azaiez, F, et al.
Publicado: (1994)

Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?
por: Langouche, Lies, et al.
Publicado: (2021)

Critical Illness–induced Corticosteroid Insufficiency: What It Is Not and What It Could Be
por: Téblick, Arno, et al.
Publicado: (2022)

A novel patient-specific 3D printed guide for accurate femoral derotation osteotomies: a case report
por: Van Genechten, Wouter, et al.
Publicado: (2023)

MiR-193a-3p and miR-193a-5p suppress the metastasis of human osteosarcoma cells by down-regulating Rab27B and SRR, respectively
por: Pu, Youguang, et al.
Publicado: (2016)

IAU Symposium 193 : Wolf-Rayet Phenomena in Massive Stars and Starburst Galaxies
por: Van der Hucht, K A, et al.
Publicado: (1998)

DNM3OS Facilitates Ovarian Cancer Progression by Regulating miR-193a-3p/MAP3K3 Axis
por: He, Lei, et al.
Publicado: (2021)

The p-adic Simpson correspondence (AM-193)
por: Abbes, Ahmed, et al.
Publicado: (2016)

193. Comparison of Survival for MSSA and MRSA Endocarditis
por: Kanyo, Emese, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_t5t3f064pvpk6as7poql3giga3