LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior

Lamins form stable filaments at the nuclear periphery in metazoans. Unlike B-type lamins, lamins A and C localize also in the nuclear interior, where they interact with lamin-associated polypeptide 2 alpha (LAP2α). Using antibody labeling, we previously observed a depletion of nucleoplasmic A-type l...

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Detalles Bibliográficos
Autores principales: Naetar, Nana, Georgiou, Konstantina, Knapp, Christian, Bronshtein, Irena, Zier, Elisabeth, Fichtinger, Petra, Dechat, Thomas, Garini, Yuval, Foisner, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939549/
https://www.ncbi.nlm.nih.gov/pubmed/33605210
http://dx.doi.org/10.7554/eLife.63476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939549/
https://www.ncbi.nlm.nih.gov/pubmed/33605210
http://dx.doi.org/10.7554/eLife.63476

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