Cargando…

LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior

Lamins form stable filaments at the nuclear periphery in metazoans. Unlike B-type lamins, lamins A and C localize also in the nuclear interior, where they interact with lamin-associated polypeptide 2 alpha (LAP2α). Using antibody labeling, we previously observed a depletion of nucleoplasmic A-type l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naetar, Nana, Georgiou, Konstantina, Knapp, Christian, Bronshtein, Irena, Zier, Elisabeth, Fichtinger, Petra, Dechat, Thomas, Garini, Yuval, Foisner, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939549/ https://www.ncbi.nlm.nih.gov/pubmed/33605210 http://dx.doi.org/10.7554/eLife.63476

Ejemplares similares

Nucleoplasmic lamins define growth-regulating functions of lamina-associated polypeptide 2α in progeria cells
por: Vidak, Sandra, et al.
Publicado: (2018)

Loss of lamin A function increases chromatin dynamics in the nuclear interior
por: Bronshtein, I., et al.
Publicado: (2015)

Lamins at the crossroads of mechanosignaling
por: Osmanagic-Myers, Selma, et al.
Publicado: (2015)

Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins
por: Vidak, Sandra, et al.
Publicado: (2015)

A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha
por: Gesson, Kevin, et al.
Publicado: (2016)

Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease()
por: Gesson, Kevin, et al.
Publicado: (2014)

Nucleoplasmic LAP2α–lamin A complexes are required to maintain a proliferative state in human fibroblasts
por: Pekovic, Vanja, et al.
Publicado: (2007)

Chromatin Viscoelasticity Measured by Local Dynamic Analysis
por: Vivante, Anat, et al.
Publicado: (2020)

The Dynamics of Lamin a During the Cell Cycle
por: Vivante, Anat, et al.
Publicado: (2021)

Exploring chromatin organization mechanisms through its dynamic properties
por: Bronshtein, Irena, et al.
Publicado: (2016)

Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons
por: Zada, D., et al.
Publicado: (2019)

LAP2α preserves genome integrity through assisting RPA deposition on damaged chromatin
por: Bao, Kaiwen, et al.
Publicado: (2022)

Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria
por: Manakanatas, Christina, et al.
Publicado: (2022)

Lamin-binding Fragment of LAP2 Inhibits Increase in Nuclear Volume during the Cell Cycle and Progression into S Phase
por: Yang, Li, et al.
Publicado: (1997)

Confocal 3D DNA Cytometry: Assessment of Required Coefficient of Variation By Computer Simulation
por: Garini, Yuval
Publicado: (2006)

Wnt4 and LAP2alpha as Pacemakers of Thymic Epithelial Senescence
por: Kvell, Krisztian, et al.
Publicado: (2010)

The final lap…
por: Manohar, Balaji
Publicado: (2013)

Lap-Robotics
Publicado: (2015)

Uniform Contraction-Expansion Description of Relative Centromere and Telomere Motion
por: Kepten, Eldad, et al.
Publicado: (2015)

Distinct 3D Structural Patterns of Lamin A/C Expression in Hodgkin and Reed-Sternberg Cells
por: Contu, Fabio, et al.
Publicado: (2018)

Strength and failure mechanism of single-lap magnesium-basalt fiber metal laminate adhesively bonded joints: Experimental and numerical assessments
por: Mottaghian, Fatemeh, et al.
Publicado: (2022)

Effect of the Lapping Platen Groove Density on the Characteristics of Microabrasive-Based Lapping
por: Lee, Taekyung, et al.
Publicado: (2020)

Monoclonal Antibodies Specific for Disease-Associated Point-Mutants: Lamin A/C R453W and R482W
por: Roblek, Marko, et al.
Publicado: (2010)

Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse
por: Osmanagic-Myers, Selma, et al.
Publicado: (2018)

Experimental and Numerical Study of Low-Velocity Impact and Tensile after Impact for CFRP Laminates Single-Lap Joints Adhesively Bonded Structure
por: Hu, Chunxing, et al.
Publicado: (2021)

The nucleoplasmic interactions among Lamin A/C-pRB-LAP2α-E2F1 are modulated by dexamethasone
por: Ricci, Anastasia, et al.
Publicado: (2021)

Modeling Progressive Damage and Failure of Single-Lap Thin-Ply-Laminated Composite-Bolted Joint Using LaRC Failure Criterion
por: Wang, Xiangjiang, et al.
Publicado: (2022)

Xenopus LAP2β protein knockdown affects location of lamin B and nucleoporins and has effect on assembly of cell nucleus and cell viability
por: Dubińska-Magiera, Magda, et al.
Publicado: (2015)

Signal processing with lapped transforms
por: Malvar, Henrique S
Publicado: (1992)

Interiors /
Publicado: (2018)

Pseudomonas putida Fis Binds to the lapF Promoter In Vitro and Represses the Expression of LapF
por: Lahesaare, Andrio, et al.
Publicado: (2014)

The transcription factor Hey and nuclear lamins specify and maintain cell identity
por: Flint Brodsly, Naama, et al.
Publicado: (2019)

Applications of the Stochastic LapH Method
por: Bulava, John, et al.
Publicado: (2013)

Non-canonical autophagy LAPs lupus
por: Simon, A K, et al.
Publicado: (2016)

A medullary centre for lapping in mice
por: Dempsey, Bowen, et al.
Publicado: (2021)

Interiores : atmosferas funcionales /
por: Haro Lebrija, Fernando de
Publicado: (2011)

Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy
por: Fichtman, Boris, et al.
Publicado: (2019)

Cell Cycle Dynamics of the Nuclear Envelope
por: Foisner, Roland
Publicado: (2003)

Conformation of ring single-stranded DNA measured by DNA origami structures
por: Roth Weizman, Efrat, et al.
Publicado: (2022)

Décima interior /
por: Reza, Germán A. de la
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_r3qm18fj3j872in4jaqe4egiiu