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From the lab to the people: major challenges in the biological treatment of Down syndrome
Down syndrome (DS) refers to a genetic condition due to the triplication of human chromosome 21. It is the most frequent autosomal trisomy. In recent years, experimental work has been conducted with the aim of removing or silencing the extra chromosome 21 (C21) in cells and normalizing genetic expre...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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AIMS Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940110/ https://www.ncbi.nlm.nih.gov/pubmed/33709029 http://dx.doi.org/10.3934/Neuroscience.2021015 |