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From the lab to the people: major challenges in the biological treatment of Down syndrome

Down syndrome (DS) refers to a genetic condition due to the triplication of human chromosome 21. It is the most frequent autosomal trisomy. In recent years, experimental work has been conducted with the aim of removing or silencing the extra chromosome 21 (C21) in cells and normalizing genetic expre...

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Detalles Bibliográficos
Autor principal:	Rondal, Jean A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AIMS Press 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940110/ https://www.ncbi.nlm.nih.gov/pubmed/33709029 http://dx.doi.org/10.3934/Neuroscience.2021015

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