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MAPKAP Kinase-2 Drives Expression of Angiogenic Factors by Tumor-Associated Macrophages in a Model of Inflammation-Induced Colon Cancer

Chronic inflammation increases the risk for colorectal cancer through a variety of mechanisms involving the tumor microenvironment. MAPK-activated protein kinase 2 (MK2), a major effector of the p38 MAPK stress and DNA damage response signaling pathway, and a critical regulator of pro-inflammatory c...

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Detalles Bibliográficos
Autores principales: Suarez-Lopez, Lucia, Kong, Yi Wen, Sriram, Ganapathy, Patterson, Jesse C., Rosenberg, Samantha, Morandell, Sandra, Haigis, Kevin M., Yaffe, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940202/
https://www.ncbi.nlm.nih.gov/pubmed/33708191
http://dx.doi.org/10.3389/fimmu.2020.607891