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DNMTs Play an Important Role in Maintaining the Pluripotency of Leukemia Inhibitory Factor-Dependent Embryonic Stem Cells

Naive pluripotency can be maintained in medium with two inhibitors plus leukemia inhibitory factor (2i/LIF) supplementation, which primarily affects canonical WNT, FGF/ERK, and JAK/STAT3 signaling. However, whether one of these three supplements alone is sufficient to maintain naive self-renewal rem...

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Detalles Bibliográficos
Autores principales: Wu, Baojiang, Li, Yunxia, Li, Bojiang, Zhang, Baojing, Wang, Yanqiu, Li, Lin, Gao, Junpeng, Fu, Yuting, Li, Shudong, Chen, Chen, Surani, M. Azim, Tang, Fuchou, Li, Xihe, Bao, Siqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940253/
https://www.ncbi.nlm.nih.gov/pubmed/33636115
http://dx.doi.org/10.1016/j.stemcr.2021.01.017