Molecular Mechanisms Underlying Ascl1-Mediated Astrocyte-to-Neuron Conversion

Direct neuronal reprogramming potentially provides valuable sources for cell-based therapies. Proneural gene Ascl1 converts astrocytes into induced neuronal (iN) cells efficiently both in vitro and in vivo. However, the underlying mechanisms are largely unknown. By combining RNA sequencing and chrom...

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Detalles Bibliográficos
Autores principales: Rao, Zhiping, Wang, Ran, Li, Sanlan, Shi, Yuhan, Mo, Licun, Han, Su'e, Yuan, Jiacheng, Jing, Naihe, Cheng, Leping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940254/
https://www.ncbi.nlm.nih.gov/pubmed/33577795
http://dx.doi.org/10.1016/j.stemcr.2021.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940254/
https://www.ncbi.nlm.nih.gov/pubmed/33577795
http://dx.doi.org/10.1016/j.stemcr.2021.01.006

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