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Molecular Mechanisms Underlying Ascl1-Mediated Astrocyte-to-Neuron Conversion
Direct neuronal reprogramming potentially provides valuable sources for cell-based therapies. Proneural gene Ascl1 converts astrocytes into induced neuronal (iN) cells efficiently both in vitro and in vivo. However, the underlying mechanisms are largely unknown. By combining RNA sequencing and chrom...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940254/ https://www.ncbi.nlm.nih.gov/pubmed/33577795 http://dx.doi.org/10.1016/j.stemcr.2021.01.006 |