Differentiation of Hypertrophic Chondrocytes from Human iPSCs for the In Vitro Modeling of Chondrodysplasias

Chondrodysplasias are hereditary diseases caused by mutations in the components of growth cartilage. Although the unfolded protein response (UPR) has been identified as a key disease mechanism in mouse models, no suitable in vitro system has been reported to analyze the pathology in humans. Here, we...

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Detalles Bibliográficos
Autores principales: Pretemer, Yann, Kawai, Shunsuke, Nagata, Sanae, Nishio, Megumi, Watanabe, Makoto, Tamaki, Sakura, Alev, Cantas, Yamanaka, Yoshihiro, Xue, Jing-Yi, Wang, Zheng, Fukiage, Kenichi, Tsukanaka, Masako, Futami, Tohru, Ikegawa, Shiro, Toguchida, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940258/
https://www.ncbi.nlm.nih.gov/pubmed/33636111
http://dx.doi.org/10.1016/j.stemcr.2021.01.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940258/
https://www.ncbi.nlm.nih.gov/pubmed/33636111
http://dx.doi.org/10.1016/j.stemcr.2021.01.014

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