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Two decades since the fetal insulin hypothesis: what have we learned from genetics?

In 1998 the fetal insulin hypothesis proposed that lower birthweight and adult-onset type 2 diabetes are two phenotypes of the same genotype. Since then, advances in research investigating the role of genetics affecting insulin secretion and action have furthered knowledge of fetal insulin-mediated...

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Detalles Bibliográficos
Autores principales: Hughes, Alice E., Hattersley, Andrew T., Flanagan, Sarah E., Freathy, Rachel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940336/
https://www.ncbi.nlm.nih.gov/pubmed/33569631
http://dx.doi.org/10.1007/s00125-021-05386-7