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Interferon Regulatory Factor 4 Regulates the Development of Polymorphonuclear Myeloid-Derived Suppressor Cells Through the Transcription of c-Myc in Cancer

The accumulation of myeloid-derived suppressor cells (MDSCs) is one of the major obstacles to achieve an appropriate anti-tumor immune response and successful tumor immunotherapy. MDSCs in tumor-bearing hosts are primarily polymorphonuclear (PMN-MDSCs). However, the mechanisms regulating the develop...

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Detalles Bibliográficos
Autores principales: Yang, Quan, Xie, Hongyan, Li, Xing, Feng, Yuanfa, Xie, Shihao, Qu, Jiale, Xie, Anqi, Zhu, Yiqiang, Zhou, Lu, Yang, Jinxue, Hu, Xiaohao, Wei, Haixia, Qiu, Huaina, Qin, Wenjuan, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940347/
https://www.ncbi.nlm.nih.gov/pubmed/33708218
http://dx.doi.org/10.3389/fimmu.2021.627072