Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation

LC3-associated phagocytosis (LAP) contributes to a wide range of cellular processes and notably to immunity. The stabilization of phagosomes by the macroautophagy machinery in human macrophages can maintain antigen presentation on MHC class II molecules. However, the molecular mechanisms involved in...

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Detalles Bibliográficos
Autores principales: Ligeon, Laure-Anne, Pena-Francesch, Maria, Vanoaica, Liliana Danusia, Núñez, Nicolás Gonzalo, Talwar, Deepti, Dick, Tobias P., Münz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940406/
https://www.ncbi.nlm.nih.gov/pubmed/33686057
http://dx.doi.org/10.1038/s41467-021-21829-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940406/
https://www.ncbi.nlm.nih.gov/pubmed/33686057
http://dx.doi.org/10.1038/s41467-021-21829-6

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