Cargando…

Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation

LC3-associated phagocytosis (LAP) contributes to a wide range of cellular processes and notably to immunity. The stabilization of phagosomes by the macroautophagy machinery in human macrophages can maintain antigen presentation on MHC class II molecules. However, the molecular mechanisms involved in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ligeon, Laure-Anne, Pena-Francesch, Maria, Vanoaica, Liliana Danusia, Núñez, Nicolás Gonzalo, Talwar, Deepti, Dick, Tobias P., Münz, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940406/ https://www.ncbi.nlm.nih.gov/pubmed/33686057 http://dx.doi.org/10.1038/s41467-021-21829-6

Ejemplares similares

Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing
por: Romao, Susana, et al.
Publicado: (2013)

Antigen Processing for MHC Class II Presentation via Autophagy
por: Münz, Christian
Publicado: (2012)

Canonical and Non-Canonical Functions of the Autophagy Machinery in MHC Restricted Antigen Presentation
por: Münz, Christian
Publicado: (2022)

Of LAP, CUPS, and DRibbles – Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation
por: Münz, Christian
Publicado: (2015)

Dual roles of Atg8−PE deconjugation by Atg4 in autophagy
por: Yu, Zhong-Qiu, et al.
Publicado: (2012)

Antigen processing for MHC presentation by autophagy
por: Münz, Christian
Publicado: (2010)

The Macroautophagy Machinery in MHC Restricted Antigen Presentation
por: Münz, Christian
Publicado: (2021)

Deconjugative α-Alkylation of Cyclohexenecarboxaldehydes: An Access to Diverse Terpenoids
por: Chahboun, Rachid, et al.
Publicado: (2021)

Natural Product Inhibitors of Ubiquitin Conjugation and Deconjugation
por: Hess, Wilfried, et al.
Publicado: (2016)

Remote stereoselective deconjugation of α,β-unsaturated esters by simple amidation reactions
por: Vishe, Mahesh, et al.
Publicado: (2015)

The Uptake and Deconjugation of Androstenone Sulfate in the Adipose Tissue of the Boar
por: Bone, Christine, et al.
Publicado: (2021)

Escape from the Phagosome: The Explanation for MHC-I Processing of Mycobacterial Antigens?
por: Harriff, Melanie J., et al.
Publicado: (2012)

Thymus dictates major histocompatibility complex (MHC) specificity and immune response gene phenotype of class II MHC-restricted T cells but not of class I MHC-restricted T cells
Publicado: (1984)

Involvement of autophagy in MHC class I antigen presentation
por: Øynebråten, Inger
Publicado: (2020)

Analysis of conjugated steroid androgens: Deconjugation, derivatisation and associated issues
por: Gomes, Rachel L., et al.
Publicado: (2009)

Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages
por: Ishisaka, Akari, et al.
Publicado: (2013)

A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination
por: Qiu, Jiazhang, et al.
Publicado: (2017)

Strategies to Target Specific Components of the Ubiquitin Conjugation/Deconjugation Machinery
por: Taylor, Neil C., et al.
Publicado: (2020)

Predicting T cell recognition of MHC class I restricted neoepitopes
por: Koşaloğlu-Yalçın, Zeynep, et al.
Publicado: (2018)

Inactivation of Digestive Proteases by Deconjugated Bilirubin and the Physiological Significance of Fasting Hyperbilirubinemia
por: Qin, Xiaofa
Publicado: (2009)

Biological monitoring of o‐toluidine in urine pretreated by an enzymatic deconjugation method
por: Eitaki, Yoko, et al.
Publicado: (2019)

Identical peptides recognized by MHC class I- and II-restricted T cells
Publicado: (1989)

Influence of DM-sensitivity on immunogenicity of MHC class II restricted antigens
por: Bernhardt, Anna Luise, et al.
Publicado: (2021)

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection
por: Buckley, Catherine M., et al.
Publicado: (2019)

The Phagosome Proteome: Insight into Phagosome Functions
por: Garin, Jérome, et al.
Publicado: (2001)

CD8(+) T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo
por: Chatterjee, Bithi, et al.
Publicado: (2019)

Glucuronidated Quercetin Lowers Blood Pressure in Spontaneously Hypertensive Rats via Deconjugation
por: Galindo, Pilar, et al.
Publicado: (2012)

Negative Regulation of TLR Inflammatory Signaling by the SUMO-deconjugating Enzyme SENP6
por: Liu, Xing, et al.
Publicado: (2013)

ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages
por: Aylan, Beren, et al.
Publicado: (2023)

Inhibition of MHC class II-restricted T cell response by Lyt-2 alloantigen
Publicado: (1989)

Toward a Network Model of MHC Class II-Restricted Antigen Processing
por: Miller, Michael A., et al.
Publicado: (2013)

Characterization of Antigenic MHC-Class-I-Restricted T Cell Epitopes in the Glycoprotein of Ebolavirus
por: Powlson, Jonathan, et al.
Publicado: (2019)

The impact of DM on MHC class II–restricted antigen presentation can be altered by manipulation of MHC–peptide kinetic stability
por: Lazarski, Christopher A., et al.
Publicado: (2006)

Phagosomal transport depends strongly on phagosome size
por: Keller, S., et al.
Publicado: (2017)

Antigen Processing by Macroautophagy for MHC Presentation
por: Münz, Christian
Publicado: (2011)

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation
por: Vieira, Otilia V., et al.
Publicado: (2001)

Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes
por: Bohdanowicz, Michal, et al.
Publicado: (2010)

An MHC class Ib–restricted CD8 T cell response confers antiviral immunity
por: Swanson, Phillip A., et al.
Publicado: (2008)

Macropinocytosis in phagocytes: regulation of MHC class-II-restricted antigen presentation in dendritic cells
por: Liu, Zhenzhen, et al.
Publicado: (2015)

Analyses of the TCR repertoire of MHC class II-restricted innate CD4(+) T cells
por: Kang, Byung Hyun, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tk55486e54v37d43q4n0rt1jk6