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A stalled-ribosome rescue factor Pth3 is required for mitochondrial translation against antibiotics in Saccharomyces cerevisiae

Mitochondrial translation appears to involve two stalled-ribosome rescue factors (srRFs). One srRF is an ICT1 protein from humans that rescues a “non-stop” type of mitochondrial ribosomes (mitoribosomes) stalled on mRNA lacking a stop codon, while the other, C12orf65, reportedly has functions that o...

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Detalles Bibliográficos
Autores principales: Hoshino, Soichiro, Kanemura, Ryohei, Kurita, Daisuke, Soutome, Yukihiro, Himeno, Hyouta, Takaine, Masak, Watanabe, Masakatsu, Nameki, Nobukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940416/
https://www.ncbi.nlm.nih.gov/pubmed/33686140
http://dx.doi.org/10.1038/s42003-021-01835-6