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Treg and Oligoclonal Expansion of Terminal Effector CD8(+) T Cell as Key Players in Multiple Myeloma

The classical paradigm of host-tumor interaction, i.e. elimination, equilibrium, and escape (EEE), is reflected in the clinical behavior of myeloma which progresses from the premalignant condition, Monoclonal Gammopathy of Unknown Significance (MGUS). Despite the role of other immune cells, CD4(+) r...

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Detalles Bibliográficos
Autores principales: Joshua, Douglas E., Vuckovic, Slavica, Favaloro, James, Lau, Ka Hei Aleks, Yang, Shihong, Bryant, Christian E., Gibson, John, Ho, Phoebe Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940512/
https://www.ncbi.nlm.nih.gov/pubmed/33708212
http://dx.doi.org/10.3389/fimmu.2021.620596