Cargando…

Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro

Perineuronal nets (PNNs) are specialized, reticular structures of the extracellular matrix (ECM) that can be found covering the soma and proximal dendrites of a neuronal subpopulation. Recent studies have shown that PNNs can highly influence synaptic plasticity and are disrupted in different neurops...

Descripción completa

Detalles Bibliográficos
Autores principales: Wegrzyn, David, Freund, Nadja, Faissner, Andreas, Juckel, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940526/
https://www.ncbi.nlm.nih.gov/pubmed/33708102
http://dx.doi.org/10.3389/fnsyn.2021.637549