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Haplotypes of FOXP3 genetic variants are associated with susceptibility, autoantibodies, and TGF-β1 in patients with systemic lupus erythematosus

The aim of this study was to evaluate the association of rs2232365 (-924 G > A) and rs3761548 (-3279 C > A) FOXP3 variants with systemic lupus erythematosus (SLE) susceptibility, TGF-β1 plasma levels, autoantibodies, and LN nephritis, and SLE disease activity index (SLEDAI). The study included...

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Detalles Bibliográficos
Autores principales: Stadtlober, Nicole Perugini, Flauzino, Tamires, da Rosa Franchi Santos, Lorena Flor, Iriyoda, Tatiana Mayumi Veiga, Costa, Neide Tomimura, Lozovoy, Marcell Alysson Batisti, Dichi, Isaias, Reiche, Edna Maria Vissoci, Simão, Andréa Name Colado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940633/
https://www.ncbi.nlm.nih.gov/pubmed/33686190
http://dx.doi.org/10.1038/s41598-021-84832-3