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Diagnostic Utility of IGF2BP1 and Its Targets as Potential Biomarkers in ETV6-RUNX1 Positive B-Cell Acute Lymphoblastic Leukemia

Around 85% of childhood Acute Lymphoblastic Leukemia (ALL) are of B-cell origin and characterized by the presence of different translocations including BCR-ABL1, ETV6-RUNX1, E2A-PBX1, and MLL fusion proteins. The current clinical investigations used to identify ETV6-RUNX1 translocation include FISH...

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Detalles Bibliográficos
Autores principales: Sharma, Gunjan, Boby, Elza, Nidhi, Thakur, Jain, Ayushi, Singh, Jay, Singh, Archna, Chattopadhyay, Parthaprasad, Bakhshi, Sameer, Chopra, Anita, Palanichamy, Jayanth Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940665/
https://www.ncbi.nlm.nih.gov/pubmed/33708624
http://dx.doi.org/10.3389/fonc.2021.588101