Cargando…

AhR/miR-23a-3p/PKCα axis contributes to memory deficits in ovariectomized and normal aging female mice

The mechanism of estrogen deficiency-induced cognitive impairment is still not fully elucidated. In this study, we assessed the effect of microRNA (miRNA) on the memory of long-term estrogen-deficient mice after ovariectomy (OVX) and normal aging. We observed that 5-month OVX and 22-month-old normal...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shuai, An, Xiaobin, Huang, Siyu, Zeng, Lu, Xu, Yi, Su, Dan, Qu, Yang, Tang, Xin, Ma, Jing, Yang, Junkai, Ai, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940705/
https://www.ncbi.nlm.nih.gov/pubmed/33738140
http://dx.doi.org/10.1016/j.omtn.2021.02.015